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The width of the QRS is often used to ascertain
2019-04-17
The width of the QRS is often used to ascertain the distance of the site of origin from the conduction system. In the absence of antiarrhythmics, which result in conduction slowing, VTs with narrow QRS are located closer to the purkinje system or septum. VTs originating from the epicardium have been
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br Case report Radiographs showed a lytic lesion in
2019-04-17
Case report Radiographs showed a lytic lesion in the left ilium adjacent to the sacroiliac joint (Fig. 1). Computed tomography (CT) (Fig. 2) showed a 5.5×5.0×3.4cm3 lytic lesion in the left ilium; the sacrum was not involved. The lesion was of uniform density with no bone or cartilage matrix form
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Heat shock facilitates the folding
2019-04-17
Heat shock facilitates the folding of various proteins as mediated by the HSP family and can stabilize mutant proteins. HS has been reported to facilitate maturation of WT-HERG as well as mutant HERG by activating the HSF family [15]. HSF-1, 2, and 4 were reported to be expressed in humans. HSF-1 is
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The other uncommon types of idiopathic VT
2019-04-16
The other uncommon types of idiopathic VT such as non-reentrant focal Purkinje VT, papillary muscle VT, and mitral/tricuspid annular VT may also present as incessant or repetitive forms of monomorphic VT. Importantly, an incessant nature of the VTs can secondarily decrease the global (not segmental)
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br Remote technologies The platforms available for remote
2019-04-16
Remote technologies The platforms available for remote monitoring of ICDs differ. Wand-based (“inductive”) systems require patient-driven downloads relayed via telephone connections to tracking facilities [4,5]. These are becoming obsolete. This is because they demand coordination with a device c
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La fundaci n de una literatura nacional nicarag
2019-04-16
La fundación de una literatura nacional nicaragüense, que ocurre durante la primera mitad del siglo xx y está 7-Nitroindazole cargo del principal grupo de vanguardia, encabezado por escritores como José Coronel Urtecho y Pablo Antonio Cuadra, presenta una aspiración popular o populista. Esta consist
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In primary diagnosis IKZF status was not taken into
2019-04-16
In primary diagnosis IKZF1 status was not taken into account for risk group stratification. According to protocol ALL-MB-2002 regulations, risk was underestimated and patient was assigned to the SRG. Prognostic value of IKZF1 alterations in ALL, especially BCR-ABL1 negative ALL, is still debated [19
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EZ Cap Reagent GG br Rheumatic heart disease RHD
2019-04-16
Rheumatic heart disease (RHD) affects over 32 million people worldwide; the vast majority of patients are in low-income and middle-income countries. It is a leading cause of premature mortality in children and young adults living in endemic regions. Patients with RHD often present in an advanced s
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National coverage trends were accelerated because of the
2019-04-16
National coverage trends were accelerated because of the contribution of trends in the two poorest quintiles. In middle-income countries, for example, the estimated increase in national trends was around 25% faster as a result of the contribution of poor populations. Increases in coverage in rural a
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The width of the QRS is often used to ascertain
2019-04-16
The width of the QRS is often used to ascertain the distance of the site of origin from the conduction system. In the absence of antiarrhythmics, which result in conduction slowing, VTs with narrow QRS are located closer to the purkinje system or septum. VTs originating from the epicardium have been
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Clinical genetic electrocardiographic and electrophysiologic
2019-04-16
Clinical, genetic, electrocardiographic, and electrophysiological variables did not differ significantly between patients with and without the ER pattern (Table 2). Discussion Among our Brugada syndrome patients, the prevalence of the ER pattern was 10.1%, which is high in comparison to the 2%–5
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lxr agonist br Materials and methods This study included WCD
2019-04-16
Materials and methods This study included WCD patients with high risk of SCD but did not meet the eligibility criteria for immediate lxr agonist of an implantable cardioverter defibrillator (ICD). Current guidelines endorse indications for WCD therapy [5]. Patients with low left ventricular ejec
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The participants discussed several overarching themes
2019-04-16
The participants discussed several overarching themes, concluding that research is too often separate from implementation. A crucial gap remains between the development of efficacious health interventions and their optimum delivery in real-life settings. This gap is particularly true in many low-inc
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br Conformational control inhibition Conformational escape
2019-04-15
Conformational control inhibition Conformational escape resistance is a phenomenon where point mutations (such as T315I) drive the Abl kinase toward the active type I state. “Switch-control inhibitors” bind in a non-ATP-competitive fashion to residues (E282, R386) the Abl protein uses to switch b
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bcr-abl inhibitor Generally patients with VVS do not need co
2019-04-15
Generally, patients with VVS do not need continuous cardiac pacing, but require physiological pacing only at the moment of the vasovagal response. Petersen et al. [7] reported the efficacy of permanent DDI pacing with rate hysteresis in selected patients who presented with cardioinhibitory VVS. Prev
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