• A diferencia de Sancho de

  2019-07-01

  

  A diferencia de Sancho de Moncada y Gerónimo de Zevallos, regidor de Toledo (ff. 150-153), que se oponen aa-dutp la naturalización de los extranjeros, Alarcón propone que quienes quieran vivir en España gocen de las preeminencias de los naturales, pues “la copia de la gente / hace poderoso al rey” (

• It must be noted that modern physical techniques for

  2019-07-01

  

  It must be noted that modern physical techniques for structural analysis of steroids were not available to these early talented scientists that time. It was a challenging task for these early scientists to precisely identify the chemical structures of cholesterol and bile acids. However, the develop

• Bile acids are cholesterol derivatives produced

  2019-07-01

  

  Bile acids are cholesterol derivatives produced only in the hepatocytes of the liver. Hepatic bile acid synthesis represents the only quantitatively significant route for cholesterol elimination. Bile acids are amphipathic physiological detergents that facilitate dietary cholesterol, lipid and fat-s

• farnesyl diphosphate synthase In Jillian Pintye and colleagu

  2019-07-01

  

  In Jillian Pintye and colleagues from the Partners PrEP study team present one of the largest and most comprehensive analyses of syphilis incidence in men and women and the effect of male circumcision. The investigators followed 4716 HIV-1 serodiscordant couples, of whom roughly 50% of the men were

• Visto el franquismo como el gran eje de la discordia

  2019-07-01

  

  Visto el franquismo como el gran eje de la discordia, el punto de in flexión se produjo en 1949 con motivo de la presentación en la onu de una propuesta conjunta de cuatro países de América Latina: Brasil, Bolivia, Colombia y Perú. La propuesta de resolución del cuatripartito latinoamericano (proyec

• In addition the TAA treated

  2019-06-29

  

  In addition, the TAA-treated groups showed a significant reduction in body weight with significantly increased liver weights and sizes compared to control rats, but NJ cotreatment reversed those defects (Table 1). The reduction in body weights could be attributed to the toxic effect of TAA throughou

• br Interaction between MSCs and immune

  2019-06-29

  

  Interaction between MSCs and immune cells MSCs have also been shown to possess broad immunoregulatory capabilities and are capable of influencing both adaptive and innate immune responses. MSCs inhibit immune Pemetrexed proliferation and maturation and suppress immune reactions both in vitro and

• WIKI4 weight In the APHRS survey most

  2019-06-29

  

  In the APHRS survey, most respondents (86%) answered that OACs were discontinued before endoscopy or surgery. With novel OACs, physicians will be able to discontinue anticoagulant therapy before the surgical procedure without concern for thrombotic complications. The APHRS survey did not investigate

• Galanthamine HBr Currently we are unable to fully understand

  2019-06-29

  

  Currently, we are unable to fully understand the Galanthamine HBr and distribution of the AT arising around the apex of the triangle of Koch. Koyama et al. closely studied the spatial and topographic variation in the distribution of this type of AT around the His-bundle [17]. As demonstrated in the

• br Methods br Results br Discussion Bisphosphonates reduce s

  2019-06-29

  

  Methods Results Discussion Bisphosphonates reduce skeletal morbidity in patients with advanced cancers involving bone and have become a recommended component of the multidisciplinary treatment of MBD [1]. However, bone-health benefits have not generally translated into significantly improve

• br In Sanguinetti et al and Barhanin

  2019-06-29

  

  In 1996, Sanguinetti et al. and Barhanin et al. independently found that, when coassembled with the accessory subunit KCNE1, the KCNQ1 and KCNE1 complex could form a channel that very closely exhibited conductive and kinetic properties similar to that of cardiac IKs[14,56]. Kass and coworkers subs

• br Conclusions br Conflict of interest

  2019-06-29

  

  Conclusions Conflict of interest Introduction Radiofrequency (RF) catheter ablation is an established method of therapy for symptomatic supraventricular tachycardia (SVT). It has gained widespread acceptance for the treatment of accessory pathways in pediatric SVTs [1]. Accessory pathways a

• Common and rare SCN A

  2019-06-29

  

  Common and rare SCN10A variants may contribute to AF susceptibility [59,60]. SCN10A mutations (R14L and R1268Q) cause a loss of function of Nav1.5 current, which is expected to reduce excitability and lead to the development of the arrhythmogenic substrate responsible for BrS and AF. A common varia

• The region is also suffering

  2019-06-29

  

  The region is also suffering from administrative negligence, extreme poverty, lack of basic health facilities, and weak infrastructure, which have increased its vulnerability to the climatic misery. Travel time to the nearest health facility is 2–4 h, at a cost of PKR 1000–4000 (US$10–40) in a regio

• The greater relative importance of

  2019-06-29

  

  The greater relative importance of indirect causes could be a result of successful addressing of direct complications of pregnancy and childbirth, and of a change in risk factors and disease patterns. Indirect causes of death include the effects of pre-existing disorders, such as HIV infection, ment

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